Lemma 66.17.5. Let $S$ be a scheme. Let $j : U \to X$ be an open immersion of algebraic spaces over $S$. Then $U$ is scheme theoretically dense in $X$ if and only if $\mathcal{O}_ X \to j_*\mathcal{O}_ U$ is injective.

**Proof.**
If $\mathcal{O}_ X \to j_*\mathcal{O}_ U$ is injective, then the same is true when restricted to any algebraic space $V$ étale over $X$. Hence the scheme theoretic closure of $U \times _ X V$ in $V$ is equal to $V$, see proof of Lemma 66.16.1. Conversely, assume the scheme theoretic closure of $U \times _ X V$ is equal to $V$ for all $V$ étale over $X$. Suppose that $\mathcal{O}_ X \to j_*\mathcal{O}_ U$ is not injective. Then we can find an affine, say $V = \mathop{\mathrm{Spec}}(A)$, étale over $X$ and a nonzero element $f \in A$ such that $f$ maps to zero in $\Gamma (V \times _ X U, \mathcal{O})$. In this case the scheme theoretic closure of $V \times _ X U$ in $V$ is clearly contained in $\mathop{\mathrm{Spec}}(A/(f))$ a contradiction.
$\square$

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