Remark 36.7.7 (Warning). Let $X$ be a quasi-compact scheme with affine diagonal. Even though we know that $D(\mathit{QCoh}(\mathcal{O}_ X)) = D_\mathit{QCoh}(\mathcal{O}_ X)$ by Proposition 36.7.5 strange things can happen and it is easy to make mistakes with this material. One pitfall is to carelessly assume that this equality means derived functors are the same. For example, suppose we have a quasi-compact open $U \subset X$. Then we can consider the higher right derived functors

of the left exact functor $\Gamma (U, -)$. Since this is a universal $\delta $-functor, and since the functors $H^ i(U, -)$ (defined for all abelian sheaves on $X$) restricted to $\mathit{QCoh}(\mathcal{O}_ X)$ form a $\delta $-functor, we obtain canonical transformations

These transformations aren't in general isomorphisms even if $X = \mathop{\mathrm{Spec}}(A)$ is affine! Namely, we have $R^1(\mathit{QCoh})\Gamma (U, \widetilde{I}) = 0$ if $I$ an injective $A$-module by construction of right derived functors and the equivalence of $\mathit{QCoh}(\mathcal{O}_ X)$ and $\text{Mod}_ A$. But Examples, Lemma 110.47.2 shows there exists $A$, $I$, and $U$ such that $H^1(U, \widetilde{I}) \not= 0$.

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